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RTK Landscape Mitochondria Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Talin Talin Talin Talin Talin Talin Talin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Rictor Rictor Rictor Rictor Rictor Mtor Mtor Mtor Mtor Mtor Mtor Mtor Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 G-beta-L G-beta-L G-beta-L Sin1 Sin1 Sin1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Raptor Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Yb1 Yb1 Yb1 Yb1 Yb1 Yb1 Yb1 Xiap Xiap Xiap Xiap Xiap Xiap Xiap p70-RSK p70-RSK p70-RSK p70-RSK p70-RSK Rictor Rictor Rictor Rictor Rictor SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma CrkL CrkL CrkL CrkL CrkL Src Src Src Src Src Src Src Src Rac1 Rac1 Rac1 Rac1 Rac1 Rac1 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Mtor Mtor Mtor Mtor Mtor Mtor Mtor Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k G-beta-L G-beta-L G-beta-L Sin1 Sin1 Sin1 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Raptor Xiap Xiap Xiap Xiap Xiap Xiap Xiap Yb1 Yb1 Yb1 Yb1 Yb1 Yb1 Yb1 p70-RSK p70-RSK p70-RSK p70-RSK p70-RSK Bak Bak Bax Bax Bax Bax Bcl2 Bcl2 Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-8-bound Caspase-8-bound Caspase-8-bound Caspase-8-bound Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 hRAS hRAS Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Spry Spry Spry Src Src Src Src Src Src Src Src Pyk2 Pyk2 Pyk2 Pyk2 Pyk2 Pyk2 Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Mek1 Mek1 Mek1 Mek1 Mek1 Mek2 Mek2 Mek2 Mek2 bRAF bRAF bRAF bRAF Ksr1 Ksr1 Ksr1 Ksr1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk2 Erk2 Erk2 Erk2 Erk2 Erk2 Erk2 p90-rsk p90-rsk p90-rsk p90-rsk p90-rsk Sos1 Sos1 Sos1 Sos1 Sos1 Sos1 Rgs14 Rgs14 Rgs14 Rac1 Rac1 Rac1 Rac1 Rac1 Rac1 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 14-3-3 14-3-3 14-3-3 14-3-3 14-3-3 Pak Pak Pak Pak Pak Pka Pka Pka Pka Pka Pka Pka Pka Pka Pka Pka Pka cRAF cRAF cRAF cRAF cRAF cRAF Spinophilin Spinophilin Spinophilin Pp1 Creb1 Creb1 Creb1 Creb1 Creb1 Creb1 Creb1 Creb1 Msk1 Msk1 Msk1 Msk1 Msk1 Msk1 Msk1 EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Epsin Epsin Epsin Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Snap25 Snap25 Snap25 Snap25 Snap25 Syntaxin1a Syntaxin1a Syntaxin1a Syntaxin1a Syntaxin1a Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Shp1 Shp1 Shp1 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 hRAS hRAS Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Socs3 Socs3 Socs3 Socs3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 Crk2 Crk2 Crk2 Crk2 Crk2 Crk2 Crk2 Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Tc10 Tc10 Tc10 Tc10 Tc10 Tc10 Tc10 Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Tug Tug Tug Tug Tug Tug Tug Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Tirap Tirap Tirap Tirap Tirap Myd88 Myd88 Myd88 Myd88 Myd88 Myd88 Myd88 Myd88 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Tab1 Tab1 Tab1 Tab1 Tab2 Tab2 Tab2 Tab2 Tab2 Tab2 Tab2 Tab2 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Mekk Mekk Mekk Mekk Mkk3 Mkk3 Mkk4 Mkk4 Mkk4 Mkk4 Mkk6 Mkk6 Mkk6 Mkk6 Mkk7 Nemo Nemo Ecsit Ecsit Ecsit Jnk1 Jnk1 Jnk1 Jnk1 Jnk1 Ikba Ikba Ikba Ikba Ikba Ikba Ikba Ikka Ikka Ikka Ikka Ikka Ikkb Ikkb Ikkb Ikkb Ikkb p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin 14-3-3 14-3-3 14-3-3 14-3-3 14-3-3 AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT AKT Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Ap2 Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin Arrestin As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 As160 Bak Bak Bax Bax Bax Bax Bcl2 Bcl2 Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-active Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-3-inactive Caspase-8-bound Caspase-8-bound Caspase-8-bound Caspase-8-bound Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-inactive Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Caspase-8-active Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-H Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Clathrin-L Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagen-IV Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Collagenase-3 Creb1 Creb1 Creb1 Creb1 Creb1 Creb1 Creb1 Creb1 Crk2 Crk2 Crk2 Crk2 Crk2 Crk2 Crk2 CrkL CrkL CrkL CrkL CrkL Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Dynamin Ecsit Ecsit Ecsit Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf Egf EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR EgfR Epsin Epsin Epsin Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk1 Erk2 Erk2 Erk2 Erk2 Erk2 Erk2 Erk2 Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fadd Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas-ligand Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fas Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn Fyn G-beta-L G-beta-L G-beta-L Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4-vesicles Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Glut4 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Gp130 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Grb2 Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Gsk3b Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Heparin Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Hip1 Ikba Ikba Ikba Ikba Ikba Ikba Ikba Ikka Ikka Ikka Ikka Ikka Ikkb Ikkb Ikkb Ikkb Ikkb Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Il6 Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin-receptor Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Insulin Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-alpha Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Integrin-beta Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak1 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak2 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irak4 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs1 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Irs2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jak2 Jnk1 Jnk1 Jnk1 Jnk1 Jnk1 Ksr1 Ksr1 Ksr1 Ksr1 Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-alpha Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-beta Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Laminin-gamma Lipid-raft Lipid-raft Lipid-raft MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-2 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 MMP-9 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mdm2 Mek1 Mek1 Mek1 Mek1 Mek1 Mek2 Mek2 Mek2 Mek2 Mekk Mekk Mekk Mekk Mkk3 Mkk3 Mkk4 Mkk4 Mkk4 Mkk4 Mkk6 Mkk6 Mkk6 Mkk6 Mkk7 Msk1 Msk1 Msk1 Msk1 Msk1 Msk1 Msk1 Mtor Mtor Mtor Mtor Mtor Mtor Mtor Myd88 Myd88 Myd88 Myd88 Myd88 Myd88 Myd88 Myd88 Nemo Nemo Nfkb-p100 Nfkb-p100 Nfkb-p100 Nfkb-p100 Nfkb-p100 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p105 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p50 Nfkb-p52 Nfkb-p52 Nfkb-p52 Nfkb-p52 Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen Nidogen PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma PLC-gamma Pak Pak Pak Pak Pak Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Pdk1 Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Perlecan Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pfkfb2 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3K-p110 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3k-p85 Pi3p Pi3p Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pip5k Pka Pka Pka Pka Pka Pka Pka Pka Pka Pka Pka Pka Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Pkc-beta Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Plectin Pp1 Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Proteasome Pyk2 Pyk2 Pyk2 Pyk2 Pyk2 Pyk2 Rac1 Rac1 Rac1 Rac1 Rac1 Rac1 Raptor RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelA RelB RelB RelB RelB Rgs14 Rgs14 Rgs14 Rictor Rictor Rictor Rictor Rictor SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SCF SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC SPARC Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shoc2 Shp1 Shp1 Shp1 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Shp2 Sin1 Sin1 Sin1 Snap25 Snap25 Snap25 Snap25 Snap25 Socs3 Socs3 Socs3 Socs3 Sos1 Sos1 Sos1 Sos1 Sos1 Sos1 Spinophilin Spinophilin Spinophilin Spry Spry Spry Src Src Src Src Src Src Src Src Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Stat3 Syntaxin1a Syntaxin1a Syntaxin1a Syntaxin1a Syntaxin1a TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 TIMP-2 Tab1 Tab1 Tab1 Tab1 Tab2 Tab2 Tab2 Tab2 Tab2 Tab2 Tab2 Tab2 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Tak1 Talin Talin Talin Talin Talin Talin Talin Tc10 Tc10 Tc10 Tc10 Tc10 Tc10 Tc10 Tirap Tirap Tirap Tirap Tirap Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr1 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Tlr2 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Traf6 Tug Tug Tug Tug Tug Tug Tug Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubc13 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin-K63 Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Ubiquitin Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Uev1a Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Vamp2 Xiap Xiap Xiap Xiap Xiap Xiap Xiap Yb1 Yb1 Yb1 Yb1 Yb1 Yb1 Yb1 bRAF bRAF bRAF bRAF c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit c-Kit cRAF cRAF cRAF cRAF cRAF cRAF hRAS hRAS p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p38-MAPK p70-RSK p70-RSK p70-RSK p70-RSK p70-RSK p90-rsk p90-rsk p90-rsk p90-rsk p90-rsk rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Integrin_B rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Plectin rtk051-adhesion_Talin rtk051-adhesion_Talin rtk051-adhesion_Talin rtk051-adhesion_Talin rtk051-adhesion_Talin rtk051-adhesion_Talin rtk051-adhesion_Talin s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r s-il6r grey background adhesion akt ckit disc ecm egf endocytosis il6 insulin toll a14-3-3 AKT Ap2 Arrestin As160 Bak Bax Bcl2 Caspase-3-active Caspase-3-inactive Caspase-8-bound Caspase-8-inactive Caspase-8-active Clathrin-H Clathrin-L Collagen-IV Collagenase-3 Creb1 Crk2 CrkL Dynamin Ecsit Egf EgfR Epsin Erk1 Erk2 Fadd Fas-ligand Fas Fyn G-beta-L Glut4-vesicles Glut4 Gp130 Grb2 Gsk3b Heparin Hip1 Ikba Ikka Ikkb aIl6 Insulin-receptor Insulin Integrin-alpha Integrin-beta Irak1 Irak2 Irak4 Irs1 Irs2 Jak2 Jnk1 Ksr1 Laminin-alpha Laminin-beta Laminin-gamma Lipid-raft MMP-2 MMP-9 Mdm2 Mek1 Mek2 Mekk Mkk3 Mkk4 Mkk6 Mkk7 Msk1 Mtor Myd88 Nemo Nfkb-p100 Nfkb-p105 Nfkb-p50 Nfkb-p52 Nidogen PLC-gamma Pak Pdk1 Perlecan Pfkfb2 Pi3K-p110 Pi3k-p85 Pi3p Pip5k Pka Pkc-beta Plectin Pp1 Proteasome Pyk2 Rac1 Raptor RelA RelB Rgs14 Rictor SCF SPARC Shoc2 Shp1 Shp2 Sin1 Snap25 Socs3 Sos1 Spinophilin Spry Src Stat3 Syntaxin1a TIMP-2 Tab1 Tab2 Tak1 Talin Tc10 Tirap Tlr1 Tlr2 Traf6 Tug Ubc13 Ubiquitin-K63 Ubiquitin Uev1a Vamp2 Xiap Yb1 bRAF c-Kit cRAF hRAS p38-MAPK p70-RSK p90-rsk rtk051-adhesion_Integrin_A rtk051-adhesion_Integrin_B rtk051-adhesion_Plectin rtk051-adhesion_Talin s-il6r